Intensive care medicine research agenda on invasive fungal infection in critically ill patients.
Identifieur interne : 000113 ( France/Analysis ); précédent : 000112; suivant : 000114Intensive care medicine research agenda on invasive fungal infection in critically ill patients.
Auteurs : Matteo Bassetti [Italie] ; Jose Garnacho-Montero [Espagne] ; Thierry Calandra [Suisse] ; Bartjan Kullberg [Pays-Bas] ; George Dimopoulos [Grèce] ; Elie Azoulay [France] ; Arunaloke Chakrabarti [Inde] ; Daniel Kett [États-Unis] ; Cristobal Leon [Espagne] ; Luis Ostrosky-Zeichner [États-Unis] ; Maurizio Sanguinetti [Italie] ; Jean-Francois Timsit [France] ; Malcom D. Richardson [Royaume-Uni] ; Andrew Shorr [États-Unis] ; Oliver A. Cornely [Allemagne]Source :
- Intensive care medicine [ 1432-1238 ] ; 2017.
Descripteurs français
- KwdFr :
- Anticorps antifongiques (sang), Antifongiques (pharmacologie), Antifongiques (usage thérapeutique), Aspergillose pulmonaire invasive (), Aspergillose pulmonaire invasive (diagnostic), Aspergillose pulmonaire invasive (mortalité), Aspergillose pulmonaire invasive (traitement médicamenteux), Aspergillus (immunologie), Aspergillus (isolement et purification), Candida (immunologie), Candida (isolement et purification), Candidémie (), Candidémie (diagnostic), Candidémie (mortalité), Candidémie (traitement médicamenteux), Essais contrôlés randomisés comme sujet, Facteurs de risque, Guides de bonnes pratiques cliniques comme sujet, Humains, Incidence, Infections fongiques invasives (), Infections fongiques invasives (imagerie diagnostique), Infections fongiques invasives (mortalité), Infections fongiques invasives (traitement médicamenteux), Maladie grave (mortalité), Marqueurs biologiques (sang), Norme de soins (normes), Recherche biomédicale, Santé mondiale, Unités de soins intensifs.
- MESH :
- diagnostic : Aspergillose pulmonaire invasive, Candidémie.
- imagerie diagnostique : Infections fongiques invasives.
- immunologie : Aspergillus, Candida.
- isolement et purification : Aspergillus, Candida.
- mortalité : Aspergillose pulmonaire invasive, Candidémie, Infections fongiques invasives, Maladie grave.
- normes : Norme de soins.
- pharmacologie : Antifongiques.
- sang : Anticorps antifongiques, Marqueurs biologiques.
- traitement médicamenteux : Aspergillose pulmonaire invasive, Candidémie, Infections fongiques invasives.
- usage thérapeutique : Antifongiques.
- Aspergillose pulmonaire invasive, Candidémie, Essais contrôlés randomisés comme sujet, Facteurs de risque, Guides de bonnes pratiques cliniques comme sujet, Humains, Incidence, Infections fongiques invasives, Recherche biomédicale, Santé mondiale, Unités de soins intensifs.
English descriptors
- KwdEn :
- Antibodies, Fungal (blood), Antifungal Agents (pharmacology), Antifungal Agents (therapeutic use), Aspergillus (immunology), Aspergillus (isolation & purification), Biomarkers (blood), Biomedical Research, Candida (immunology), Candida (isolation & purification), Candidemia (diagnosis), Candidemia (drug therapy), Candidemia (mortality), Candidemia (prevention & control), Critical Illness (mortality), Global Health, Humans, Incidence, Intensive Care Units, Invasive Fungal Infections (diagnostic imaging), Invasive Fungal Infections (drug therapy), Invasive Fungal Infections (mortality), Invasive Fungal Infections (prevention & control), Invasive Pulmonary Aspergillosis (diagnosis), Invasive Pulmonary Aspergillosis (drug therapy), Invasive Pulmonary Aspergillosis (mortality), Invasive Pulmonary Aspergillosis (prevention & control), Practice Guidelines as Topic, Randomized Controlled Trials as Topic, Risk Factors, Standard of Care (standards).
- MESH :
- chemical , blood : Antibodies, Fungal, Biomarkers.
- chemical , pharmacology : Antifungal Agents.
- chemical , therapeutic use : Antifungal Agents.
- diagnosis : Candidemia, Invasive Pulmonary Aspergillosis.
- diagnostic imaging : Invasive Fungal Infections.
- drug therapy : Candidemia, Invasive Fungal Infections, Invasive Pulmonary Aspergillosis.
- immunology : Aspergillus, Candida.
- isolation & purification : Aspergillus, Candida.
- mortality : Candidemia, Critical Illness, Invasive Fungal Infections, Invasive Pulmonary Aspergillosis.
- prevention & control : Candidemia, Invasive Fungal Infections, Invasive Pulmonary Aspergillosis.
- standards : Standard of Care.
- Biomedical Research, Global Health, Humans, Incidence, Intensive Care Units, Practice Guidelines as Topic, Randomized Controlled Trials as Topic, Risk Factors.
Abstract
To describe concisely the current standards of care, major recent advances, common beliefs that have been contradicted by recent trials, areas of uncertainty, and clinical studies that need to be performed over the next decade and their expected outcomes with regard to Candida and Aspergillus infections in non-neutropenic patients in the ICU setting.
DOI: 10.1007/s00134-017-4731-2
PubMed: 28255613
Affiliations:
- Allemagne, Espagne, France, Grèce, Inde, Italie, Pays-Bas, Royaume-Uni, Suisse, États-Unis
- Angleterre, Attique (région), Canton de Vaud, Floride, Grand Manchester, Gueldre, Latium, Texas, Washington (État), Île-de-France
- Athènes, Houston, Lausanne, Manchester, Nimègue, Paris, Rome
- Université de Manchester
Links toward previous steps (curation, corpus...)
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- to stream France, to step Extraction: 000113
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pubmed:28255613Le document en format XML
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Miller School of Medicine at the University of Miami, Miami, FL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Pulmonary and Critical Care Medicine, The Leonard M. Miller School of Medicine at the University of Miami, Miami, FL</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Leon, Cristobal" sort="Leon, Cristobal" uniqKey="Leon C" first="Cristobal" last="Leon">Cristobal Leon</name><affiliation wicri:level="1"><nlm:affiliation>Intensive Care Unit, Hospital Universitario de Valme, Universidad de Sevilla, Seville, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Intensive Care Unit, Hospital Universitario de Valme, Universidad de Sevilla, Seville</wicri:regionArea><wicri:noRegion>Seville</wicri:noRegion></affiliation></author><author><name sortKey="Ostrosky Zeichner, Luis" sort="Ostrosky Zeichner, Luis" uniqKey="Ostrosky Zeichner L" first="Luis" last="Ostrosky-Zeichner">Luis Ostrosky-Zeichner</name><affiliation wicri:level="3"><nlm:affiliation>Division of Infectious Diseases, McGovern Medical School, UTHealth, Houston, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Infectious Diseases, McGovern Medical School, UTHealth, Houston</wicri:regionArea><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Sanguinetti, Maurizio" sort="Sanguinetti, Maurizio" uniqKey="Sanguinetti M" first="Maurizio" last="Sanguinetti">Maurizio Sanguinetti</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Microbiology, Università Cattolica del Sacro Cuore, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Microbiology, Università Cattolica del Sacro Cuore, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Timsit, Jean Francois" sort="Timsit, Jean Francois" uniqKey="Timsit J" first="Jean-Francois" last="Timsit">Jean-Francois Timsit</name><affiliation wicri:level="3"><nlm:affiliation>1UMR1137-IAMETeam 5, Decision Sciences in Infectious Disease Prevention, Control and Care, Paris Diderot University-Inserm, Sorbonne Paris Cité and 2AP-HP, Medical and Infectious Diseases ICU, Bichat Hospital, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>1UMR1137-IAMETeam 5, Decision Sciences in Infectious Disease Prevention, Control and Care, Paris Diderot University-Inserm, Sorbonne Paris Cité and 2AP-HP, Medical and Infectious Diseases ICU, Bichat Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Richardson, Malcom D" sort="Richardson, Malcom D" uniqKey="Richardson M" first="Malcom D" last="Richardson">Malcom D. Richardson</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Shorr, Andrew" sort="Shorr, Andrew" uniqKey="Shorr A" first="Andrew" last="Shorr">Andrew Shorr</name><affiliation wicri:level="2"><nlm:affiliation>Pulmonary and Critical Care Medicine, Medstar Washington Hospital Center, Washington, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Pulmonary and Critical Care Medicine, Medstar Washington Hospital Center, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Cornely, Oliver A" sort="Cornely, Oliver A" uniqKey="Cornely O" first="Oliver A" last="Cornely">Oliver A. Cornely</name><affiliation wicri:level="1"><nlm:affiliation>Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Clinical Trials Centre Cologne (ZKS Köln), Department I of Internal Medicine, German Centre for Infection Research (DZIF), University of Cologne, Cologne, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Clinical Trials Centre Cologne (ZKS Köln), Department I of Internal Medicine, German Centre for Infection Research (DZIF), University of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28255613</idno><idno type="pmid">28255613</idno><idno 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ill patients.</title><author><name sortKey="Bassetti, Matteo" sort="Bassetti, Matteo" uniqKey="Bassetti M" first="Matteo" last="Bassetti">Matteo Bassetti</name><affiliation wicri:level="1"><nlm:affiliation>Infectious Diseases Clinic, Santa Maria Misericordia Hospital, University of Udine, Udine, Italy. mattba@tin.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Infectious Diseases Clinic, Santa Maria Misericordia Hospital, University of Udine, Udine</wicri:regionArea><wicri:noRegion>Udine</wicri:noRegion></affiliation></author><author><name sortKey="Garnacho Montero, Jose" sort="Garnacho Montero, Jose" uniqKey="Garnacho Montero J" first="Jose" last="Garnacho-Montero">Jose Garnacho-Montero</name><affiliation wicri:level="1"><nlm:affiliation>Unidad Clínica de Cuidados Intensivos, Hospital Universitario Virgen Macarena and Institute of Biomedicine of Seville, IBiS/CSIC/University of Seville, seville, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Unidad Clínica de Cuidados Intensivos, Hospital Universitario Virgen Macarena and Institute of Biomedicine of Seville, IBiS/CSIC/University of Seville, seville</wicri:regionArea><wicri:noRegion>seville</wicri:noRegion></affiliation></author><author><name sortKey="Calandra, Thierry" sort="Calandra, Thierry" uniqKey="Calandra T" first="Thierry" last="Calandra">Thierry Calandra</name><affiliation wicri:level="3"><nlm:affiliation>Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Kullberg, Bartjan" sort="Kullberg, Bartjan" uniqKey="Kullberg B" first="Bartjan" last="Kullberg">Bartjan Kullberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Dimopoulos, George" sort="Dimopoulos, George" uniqKey="Dimopoulos G" first="George" last="Dimopoulos">George Dimopoulos</name><affiliation wicri:level="3"><nlm:affiliation>Department of Critical Care, University Hospital ATTIKON, National and Kapodistrian University of Athens, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Critical Care, University Hospital ATTIKON, National and Kapodistrian University of Athens, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Azoulay, Elie" sort="Azoulay, Elie" uniqKey="Azoulay E" first="Elie" last="Azoulay">Elie Azoulay</name><affiliation wicri:level="3"><nlm:affiliation>Medical Intensive Care Unit, Hôpital Saint-Louis, ECSTRA Team, Biostatistics and Clinical Epidemiology, Paris Diderot Sorbonne University, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Medical Intensive Care Unit, Hôpital Saint-Louis, ECSTRA Team, Biostatistics and Clinical Epidemiology, Paris Diderot Sorbonne University, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Chakrabarti, Arunaloke" sort="Chakrabarti, Arunaloke" uniqKey="Chakrabarti A" first="Arunaloke" last="Chakrabarti">Arunaloke Chakrabarti</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh</wicri:regionArea><wicri:noRegion>Chandigarh</wicri:noRegion></affiliation></author><author><name sortKey="Kett, Daniel" sort="Kett, Daniel" uniqKey="Kett D" first="Daniel" last="Kett">Daniel Kett</name><affiliation wicri:level="2"><nlm:affiliation>Division of Pulmonary and Critical Care Medicine, The Leonard M. Miller School of Medicine at the University of Miami, Miami, FL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Pulmonary and Critical Care Medicine, The Leonard M. Miller School of Medicine at the University of Miami, Miami, FL</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Leon, Cristobal" sort="Leon, Cristobal" uniqKey="Leon C" first="Cristobal" last="Leon">Cristobal Leon</name><affiliation wicri:level="1"><nlm:affiliation>Intensive Care Unit, Hospital Universitario de Valme, Universidad de Sevilla, Seville, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Intensive Care Unit, Hospital Universitario de Valme, Universidad de Sevilla, Seville</wicri:regionArea><wicri:noRegion>Seville</wicri:noRegion></affiliation></author><author><name sortKey="Ostrosky Zeichner, Luis" sort="Ostrosky Zeichner, Luis" uniqKey="Ostrosky Zeichner L" first="Luis" last="Ostrosky-Zeichner">Luis Ostrosky-Zeichner</name><affiliation wicri:level="3"><nlm:affiliation>Division of Infectious Diseases, McGovern Medical School, UTHealth, Houston, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Infectious Diseases, McGovern Medical School, UTHealth, Houston</wicri:regionArea><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Sanguinetti, Maurizio" sort="Sanguinetti, Maurizio" uniqKey="Sanguinetti M" first="Maurizio" last="Sanguinetti">Maurizio Sanguinetti</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Microbiology, Università Cattolica del Sacro Cuore, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Microbiology, Università Cattolica del Sacro Cuore, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Timsit, Jean Francois" sort="Timsit, Jean Francois" uniqKey="Timsit J" first="Jean-Francois" last="Timsit">Jean-Francois Timsit</name><affiliation wicri:level="3"><nlm:affiliation>1UMR1137-IAMETeam 5, Decision Sciences in Infectious Disease Prevention, Control and Care, Paris Diderot University-Inserm, Sorbonne Paris Cité and 2AP-HP, Medical and Infectious Diseases ICU, Bichat Hospital, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>1UMR1137-IAMETeam 5, Decision Sciences in Infectious Disease Prevention, Control and Care, Paris Diderot University-Inserm, Sorbonne Paris Cité and 2AP-HP, Medical and Infectious Diseases ICU, Bichat Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Richardson, Malcom D" sort="Richardson, Malcom D" uniqKey="Richardson M" first="Malcom D" last="Richardson">Malcom D. Richardson</name><affiliation wicri:level="4"><nlm:affiliation>Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Shorr, Andrew" sort="Shorr, Andrew" uniqKey="Shorr A" first="Andrew" last="Shorr">Andrew Shorr</name><affiliation wicri:level="2"><nlm:affiliation>Pulmonary and Critical Care Medicine, Medstar Washington Hospital Center, Washington, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Pulmonary and Critical Care Medicine, Medstar Washington Hospital Center, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Cornely, Oliver A" sort="Cornely, Oliver A" uniqKey="Cornely O" first="Oliver A" last="Cornely">Oliver A. Cornely</name><affiliation wicri:level="1"><nlm:affiliation>Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Clinical Trials Centre Cologne (ZKS Köln), Department I of Internal Medicine, German Centre for Infection Research (DZIF), University of Cologne, Cologne, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Clinical Trials Centre Cologne (ZKS Köln), Department I of Internal Medicine, German Centre for Infection Research (DZIF), University of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author></analytic><series><title level="j">Intensive care medicine</title><idno type="eISSN">1432-1238</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antibodies, Fungal (blood)</term><term>Antifungal Agents (pharmacology)</term><term>Antifungal Agents (therapeutic use)</term><term>Aspergillus (immunology)</term><term>Aspergillus (isolation & purification)</term><term>Biomarkers (blood)</term><term>Biomedical Research</term><term>Candida (immunology)</term><term>Candida (isolation & purification)</term><term>Candidemia (diagnosis)</term><term>Candidemia (drug therapy)</term><term>Candidemia (mortality)</term><term>Candidemia (prevention & control)</term><term>Critical Illness (mortality)</term><term>Global Health</term><term>Humans</term><term>Incidence</term><term>Intensive Care Units</term><term>Invasive Fungal Infections (diagnostic imaging)</term><term>Invasive Fungal Infections (drug therapy)</term><term>Invasive Fungal Infections (mortality)</term><term>Invasive Fungal Infections (prevention & control)</term><term>Invasive Pulmonary Aspergillosis (diagnosis)</term><term>Invasive Pulmonary Aspergillosis (drug therapy)</term><term>Invasive Pulmonary Aspergillosis (mortality)</term><term>Invasive Pulmonary Aspergillosis (prevention & control)</term><term>Practice Guidelines as Topic</term><term>Randomized Controlled Trials as Topic</term><term>Risk Factors</term><term>Standard of Care (standards)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Anticorps antifongiques (sang)</term><term>Antifongiques (pharmacologie)</term><term>Antifongiques (usage thérapeutique)</term><term>Aspergillose pulmonaire invasive ()</term><term>Aspergillose pulmonaire invasive (diagnostic)</term><term>Aspergillose pulmonaire invasive (mortalité)</term><term>Aspergillose pulmonaire invasive (traitement médicamenteux)</term><term>Aspergillus (immunologie)</term><term>Aspergillus (isolement et purification)</term><term>Candida (immunologie)</term><term>Candida (isolement et purification)</term><term>Candidémie ()</term><term>Candidémie (diagnostic)</term><term>Candidémie (mortalité)</term><term>Candidémie (traitement médicamenteux)</term><term>Essais contrôlés randomisés comme sujet</term><term>Facteurs de risque</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Incidence</term><term>Infections fongiques invasives ()</term><term>Infections fongiques invasives (imagerie diagnostique)</term><term>Infections fongiques invasives (mortalité)</term><term>Infections fongiques invasives (traitement médicamenteux)</term><term>Maladie grave (mortalité)</term><term>Marqueurs biologiques (sang)</term><term>Norme de soins (normes)</term><term>Recherche biomédicale</term><term>Santé mondiale</term><term>Unités de soins intensifs</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Fungal</term><term>Biomarkers</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Antifungal Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antifungal Agents</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Candidemia</term><term>Invasive Pulmonary Aspergillosis</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Aspergillose pulmonaire invasive</term><term>Candidémie</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Invasive Fungal Infections</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Candidemia</term><term>Invasive Fungal Infections</term><term>Invasive Pulmonary Aspergillosis</term></keywords><keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Infections fongiques invasives</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Aspergillus</term><term>Candida</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Aspergillus</term><term>Candida</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Aspergillus</term><term>Candida</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Aspergillus</term><term>Candida</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Candidemia</term><term>Critical Illness</term><term>Invasive Fungal Infections</term><term>Invasive Pulmonary Aspergillosis</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Aspergillose pulmonaire invasive</term><term>Candidémie</term><term>Infections fongiques invasives</term><term>Maladie grave</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Norme de soins</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Antifongiques</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Candidemia</term><term>Invasive Fungal Infections</term><term>Invasive Pulmonary Aspergillosis</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antifongiques</term><term>Marqueurs biologiques</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Standard of Care</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Aspergillose pulmonaire invasive</term><term>Candidémie</term><term>Infections fongiques invasives</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antifongiques</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Biomedical Research</term><term>Global Health</term><term>Humans</term><term>Incidence</term><term>Intensive Care Units</term><term>Practice Guidelines as Topic</term><term>Randomized Controlled Trials as Topic</term><term>Risk Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Aspergillose pulmonaire invasive</term><term>Candidémie</term><term>Essais contrôlés randomisés comme sujet</term><term>Facteurs de risque</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Incidence</term><term>Infections fongiques invasives</term><term>Recherche biomédicale</term><term>Santé mondiale</term><term>Unités de soins intensifs</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To describe concisely the current standards of care, major recent advances, common beliefs that have been contradicted by recent trials, areas of uncertainty, and clinical studies that need to be performed over the next decade and their expected outcomes with regard to Candida and Aspergillus infections in non-neutropenic patients in the ICU setting.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Espagne</li><li>France</li><li>Grèce</li><li>Inde</li><li>Italie</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suisse</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Attique (région)</li><li>Canton de Vaud</li><li>Floride</li><li>Grand Manchester</li><li>Gueldre</li><li>Latium</li><li>Texas</li><li>Washington (État)</li><li>Île-de-France</li></region><settlement><li>Athènes</li><li>Houston</li><li>Lausanne</li><li>Manchester</li><li>Nimègue</li><li>Paris</li><li>Rome</li></settlement><orgName><li>Université de Manchester</li></orgName></list><tree><country name="Italie"><noRegion><name sortKey="Bassetti, Matteo" sort="Bassetti, Matteo" uniqKey="Bassetti M" first="Matteo" last="Bassetti">Matteo Bassetti</name></noRegion><name sortKey="Sanguinetti, Maurizio" sort="Sanguinetti, Maurizio" uniqKey="Sanguinetti M" first="Maurizio" last="Sanguinetti">Maurizio Sanguinetti</name></country><country name="Espagne"><noRegion><name sortKey="Garnacho Montero, Jose" sort="Garnacho Montero, Jose" uniqKey="Garnacho Montero J" first="Jose" last="Garnacho-Montero">Jose Garnacho-Montero</name></noRegion><name sortKey="Leon, Cristobal" sort="Leon, Cristobal" uniqKey="Leon C" first="Cristobal" last="Leon">Cristobal Leon</name></country><country name="Suisse"><region name="Canton de Vaud"><name sortKey="Calandra, Thierry" sort="Calandra, Thierry" uniqKey="Calandra T" first="Thierry" last="Calandra">Thierry Calandra</name></region></country><country name="Pays-Bas"><region name="Gueldre"><name sortKey="Kullberg, Bartjan" sort="Kullberg, Bartjan" uniqKey="Kullberg B" first="Bartjan" last="Kullberg">Bartjan Kullberg</name></region></country><country name="Grèce"><region name="Attique (région)"><name sortKey="Dimopoulos, George" sort="Dimopoulos, George" uniqKey="Dimopoulos G" first="George" last="Dimopoulos">George Dimopoulos</name></region></country><country name="France"><region name="Île-de-France"><name sortKey="Azoulay, Elie" sort="Azoulay, Elie" uniqKey="Azoulay E" first="Elie" last="Azoulay">Elie Azoulay</name></region><name sortKey="Timsit, Jean Francois" sort="Timsit, Jean Francois" uniqKey="Timsit J" first="Jean-Francois" last="Timsit">Jean-Francois Timsit</name></country><country name="Inde"><noRegion><name sortKey="Chakrabarti, Arunaloke" sort="Chakrabarti, Arunaloke" uniqKey="Chakrabarti A" first="Arunaloke" last="Chakrabarti">Arunaloke Chakrabarti</name></noRegion></country><country name="États-Unis"><region name="Floride"><name sortKey="Kett, Daniel" sort="Kett, Daniel" uniqKey="Kett D" first="Daniel" last="Kett">Daniel Kett</name></region><name sortKey="Ostrosky Zeichner, Luis" sort="Ostrosky Zeichner, Luis" uniqKey="Ostrosky Zeichner L" first="Luis" last="Ostrosky-Zeichner">Luis Ostrosky-Zeichner</name><name sortKey="Shorr, Andrew" sort="Shorr, Andrew" uniqKey="Shorr A" first="Andrew" last="Shorr">Andrew Shorr</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Richardson, Malcom D" sort="Richardson, Malcom D" uniqKey="Richardson M" first="Malcom D" last="Richardson">Malcom D. Richardson</name></region></country><country name="Allemagne"><noRegion><name sortKey="Cornely, Oliver A" sort="Cornely, Oliver A" uniqKey="Cornely O" first="Oliver A" last="Cornely">Oliver A. Cornely</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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